Places like the Ronald McDonald House or Gilda's Club accepts new items.
Certain tools may be donated to The Bodgery.
Certain art supplies could go to the Hello Art Hatchery.
Buttons, zippers, and yarn may be donated to the Textile Arts Center of Madison.
Sewing supplies can go to The Sewing Machine Project.
And on and on...
Our community is full of opportunities - you just need to do a little bit of research.
Search online for "resale shops" or "thrift stores" or "donate" plus the item you would like to give away (for example, "donate toys") should reveal additional local resources.